NUCLEIC ACID SYNTHESIS IN PSEUDOMONAS P

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Nucleic Acid Synthesis

INTRODUCTION Synthesis in the field of nucleic acids has been a major and continuing interest in my laboratory ever since we knew the structures of the nucleic acids. Clearly the foundations of synthetic work in the nucleotide field were laid by the prolonged and intensive efforts of Professor Todd's laboratory (Cambridge, England) and it was my good fortune to be associated with this laborator...

متن کامل

Synthesis of protein and nucleic acid by disrupted spheroplasts of Pseudomonas schuylkilliensis.

Osmotically shocked spheroplasts obtained from Pseudomonas schuylkilliensis strain P contained about 54, 32, 28, and 82% of the total cellular protein, ribonucleic acid (RNA), deoxyribonucleic acid (DNA), and phospholipid, respectively. This preparation was capable of incorporating (32)P-orthophosphate into RNA and DNA, (3)H-adenosine or (3)H-uridine into RNA, and (3)H-leucine or (14)C-phenylal...

متن کامل

Organometallic methodologies for nucleic acid synthesis

A new, general preparation of 2'-5'-linked oligoadenylates has been developed, which relies on: (1) chemoselective 0phosphorylation of N-unblocked nucleosides via hydroxyl activation by Grignard reagents, (2) one-pot construction of internucleotide linkage using bifunctional phosphorylating agents, and (3) selective production of a 3',5'-di-O-protected adenosine. This solution-phase synthesis a...

متن کامل

The inhibition of nucleic acid synthesis by mycophenolic acid.

1. Mycophenolic acid, an antibiotic of some antiquity that more recently has been found to have marked activity against a range of tumours in mice and rats, strongly inhibits DNA synthesis in the L strain of fibroblasts in vitro. 2. The extent of the inhibition of DNA synthesis is markedly increased by preincubation of the cells with mycophenolic acid before the addition of [(14)C]thymidine. 3....

متن کامل

Inhibition of Nucleic Acid Synthesis by Folie Acid Antagonists*

Woolley and Pringle (13) have recently reported the formation of 4-amino-5-carboxamidoimidazole during growth of Escherichia coli in the presence of 4-aminopteroylglutainic acid (aminopterin). Some of us have observed that excessive doses of folie acid speed up the leukemic process in mice and that folie acid will reverse the well known antileukemic action of aminopterin (11). This reversal of ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: The Journal of General and Applied Microbiology

سال: 1965

ISSN: 1349-8037,0022-1260

DOI: 10.2323/jgam.11.71